Full Metal Alchemist

Two young brothers, Edward and Alphonse Elric attempt unsuccessfully to revive their mother using the power of alchemy. In the process, the elder brother, Ed, loses a leg, and the younger brother, Al, loses his entire body. Ed manages to attach his brother's soul to a nearby suit of armor, at the cost of his right arm.

This is the story of the Elric brothers as they set off to find a means to regain their original and complete bodies.